Total Synthesis of (.+-.)-Acetomycin and Design of Esterase-Resistant Analogs.

J Uenishi, N Kobayashi, S Komine, T Okadai…

文献索引：Uenishi; Kobayashi; Komine; Okadai; Yonemitsu; Sasaki; Yamada Chemical and pharmaceutical bulletin, 1999 , vol. 47, # 4 p. 517 - 523

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被引用次数: 7

摘要

The synthesis of acetomycin and related analogs was investigated. Acetomycin was synthesized from diethyl allyl (methyl) malonate in 6.5% yield over 18 steps. The total number of steps was improved compared to our previous synthesis; ie, four steps shorter, ...