Analogs of pteroylglutamic acid. V. 4-Alkylamino derivatives

B Roth, JM Smith Jr, ME Hultquist

文献索引：Roth et al. Journal of the American Chemical Society, 1950 , vol. 72, p. 1914,1917

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被引用次数: 24

摘要

Summary Partial hydrolysis of the diacetate of Abpregnendiol-3, 21-one-20 removes the 21- acetoxy group. Treatment of this product with thionyl chloride gave 21-chloropregnenol-3- one-20 acetate, an intermediate in the preparation of desoxycorticosterone acetate by known methods. Several different esters on Csl of the% monoacetate of A5-pregnendiol-3, 21-one-20 have been prepared. The partial saponification of all these products invariably ...