Reversing the Reactivity of Carbonyl Functions with Phosphonium Salts: Enantioselective Total Synthesis of (+)??Centrolobine

H Fujioka, K Yahata, O Kubo, Y Sawama…

文献索引：Fujioka, Hiromichi; Yahata, Kenzo; Kubo, Ozora; Sawama, Yoshinari; Hamada, Tomohito; Maegawa, Tomohiro Angewandte Chemie - International Edition, 2011 , vol. 50, # 51 p. 12232 - 12235

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被引用次数: 23

摘要

The control of chemoselective transformations irrespective of the individual reactivity of functional groups still remains a largely unanswered challenge. Carbonyl groups, such as aldehydes and ketones, are without doubt the most important functional groups in organic chemistry and their reactions are well known. The order of the reactivity of carbonyl groups toward nucleophiles is generally aldehyde> ketone> ester. Therefore, it is easy to react an ...