A series of naphthamides were synthesized, and the affinities of these compounds were determined for dopamine D2 and D3 receptors using radioligand binding techniques. The naphthamide compounds that were prepared include N-(1-alkylpiperidin-4-yl)-4-bromo-1- methoxy-2-naphthamides (1-6),(S)-N-(1-alkylpyrrolidin-3-yl)-4-bromo-1-methoxy-2- naphthamides (7-12),(R)-N-(1-alkylpyrrolidin-3-yl)-4-bromo-1-methoxy-2-naphthamides ( ...
