Journal of fluorine chemistry

A new method for making acyl fluorides using BrF 3

O Cohen, R Sasson, S Rozen

文献索引：Cohen, Or; Sasson, Revital; Rozen, Shlomo Journal of Fluorine Chemistry, 2006 , vol. 127, # 3 p. 433 - 436

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被引用次数: 16

摘要

While many carboxylic acids could be converted directly to acyl fluorides by using BrF3, the reaction with acyl chlorides was found to be of a more general nature and yields better results. Surprisingly, reacting t-butyl esters with bromine trifluoride also resulted in acyl fluorides in reasonable yields. The reactions were completed in a few seconds at 0° C.