A Facile Synthesis of Substituted Indenones and Piperidine??2, 6??diones from the Baylis–Hillman Acetates

D Basavaiah, DV Lenin

文献索引：Basavaiah, Deevi; Lenin, Dandamudi V. European Journal of Organic Chemistry, 2010 , # 29 p. 5650 - 5658

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被引用次数: 8

摘要

The ind-2-en-1-one framework represents an important class of carbocyclic molecules, and many of these derivatives are found in important natural products.1 Some of indenone derivatives are also known to be peroxisome proliferator-activated receptor γ (PPAR γ, drug used against type-2 diabetes) agonists,2a,2b estrogen receptor binding agents,2c,2d cyclooxygenase-2 inhibitors,2e and potent reversible inhibitors of 3CP.2f Due to their significant medicinal ...