Electroreductive coupling of trifluoromethylarenes with electrophiles: synthetic applications

C Saboureau, M Troupel, S Sibille…

文献索引：Saboureau, Christophe; Troupel, Michel; Sibille, Soline; Perichon, Jacques Journal of the Chemical Society, Chemical Communications, 1989 , # 16 p. 1138 - 1139

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被引用次数: 30

摘要

Molecules bearing an ArCH2 group (Ar = aromatic), such as arylacetic acids and related compounds, are used in phar- maceutical or agrochemical fields. The presence of two fluorine atoms on the benzylic carbon is expected to modify the biological activity and the potential interest of these fluorosubstituted compounds is then evident. Unfortunately, methods allowing the synthesis of these ArCF2 derivatives are scarce and inconvenient ,I since trifluoromethylarenes ( ...