Exploiting phosphonate chemistry in metal-mediated dearomatization: Stereoselective construction of functionalized spirolactams from arene ruthenium complexes
FC Pigge, JJ Coniglio, R Dalvi
文献索引：Pigge, F. Christopher; Coniglio, John J.; Dalvi, Rashmi Journal of the American Chemical Society, 2006 , vol. 128, # 11 p. 3498 - 3499
Arene ruthenium complexes possessing β-amido phosphonate side chains participate in intramolecular spirocyclization reactions to deliver stable cyclohexadienyl ruthenium adducts. Spirocyclization is accomplished via a tandem two-step sequence that involves stereoselective nucleophilic aromatic addition to the ipso position of the coordinated arene, followed by intermolecular Horner-Wadsworth-Emmons olefination. The resulting η5- ...
