Archiv der Pharmazie

Synthesis, Molecular Modelling and Biological Evaluation of 4??Amino??2 (1H)??quinazolinone and 2, 4 (1H, 3H)??Quinazolidone Derivatives as Antitumor Agents

S Richter, B Gioffreda

文献索引：Richter, Stephanie; Gioffreda, Barbara Archiv der Pharmazie, 2011 , vol. 344, # 12 p. 810 - 820

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被引用次数: 5

摘要

Cancer poses a serious human health problem despite much progress in understanding its biology and pharmacology. Consequently, the design of new lead structures of antitumor agents is one of the most urgent research areas in contemporary medicinal chemistry. Among the wide range of pharmacologically active heterocycles some have attracted great attention as potential chemotherapeutic agents 1–3. In the last years anticancer drug strategies involve molecular targets which ...