An extremely powerful acylation reaction of alcohols with acid anhydrides catalyzed by trimethylsilyl trifluoromethanesulfonate

PA Procopiou, SPD Baugh, SS Flack…

文献索引：Procopiou, Panayiotis A.; Baugh, Simon P.D.; Flack, Stephen S.; Inglis, Graham G.A. Journal of Organic Chemistry, 1998 , vol. 63, # 7 p. 2342 - 2347

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被引用次数: 246

摘要

Trimethylsilyl trifluoromethanesulfonate is an excellent catalyst for the acylation of alcohols with acid anhydrides. Highly functionalized primary, secondary, tertiary, and allylic alcohols, and phenols, were acylated cleanly and efficiently and in a fraction of the time used under the standard DMAP conditions.