Tetrahedron Letters

Total synthesis of pulverolide: revision of its structure

W Yang, J Liu, H Zhang

文献索引：Yang, Wanqiu; Liu, Jikai; Zhang, Hongbin Tetrahedron Letters, 2010 , vol. 51, # 37 p. 4874 - 4876

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被引用次数: 9

摘要

A flexible and practical strategy toward the synthesis of rare 2H-furo [3, 2-b] benzopyran-2- one skeleton has been developed. With a microwave-assisted cyclization–dehydration as the key transformation, the first total synthesis of pulverolide has been completed in 10 steps with 9% overall yield, leading to the revision of its proposed structure.