Microwave-assisted synthesis of pyrido [1, 2-a] benzimidazole derivatives of β-aryloxyquinoline and their antimicrobial and antituberculosis activities

CB Sangani, HH Jardosh, MP Patel…

文献索引：Sangani, Chetan B.; Jardosh, Hardik H.; Patel, Manish P.; Patel, Ranjan G. Medicinal Chemistry Research, 2013 , vol. 22, # 6 p. 3035 - 3047

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被引用次数: 14

摘要

Abstract A new series containing pyrido [1, 2-a] benzimidazole derivatives of β- aryloxyquinoline has been synthesized via base catalyzed microwave-assisted multi- component cyclocondensation reaction. This methodology allowed us to achieve the desired products in good yields in very short time with the use of 10 mol% NaOH as a non- hazardous organic base. The chemical structures of compounds 6a–x were elucidated by ...