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Tetrahedron

A simple metal-free synthesis of 2-substituted pyridine-4, 5-dicarboxylates and their N-oxides

J Bezenšek, B Prek, U Grošelj, M Kasunič, J Svete…

文献索引:Bezensek, Jure; Prek, Benjamin; Groselj, Uros; Kasunic, Marta; Svete, Jurij; Stanovnik, Branko Tetrahedron, 2012 , vol. 68, # 24 p. 4719 - 4731

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被引用次数: 16

摘要

Herein a simple, metal-free synthesis of 2-alkyl-, 2-cycloalkyl-, 2-aryl-, and 2-heteroaryl- substituted pyridine 3, 4-dicarboxylates and their N-oxides from the corresponding methyl ketones in good to excellent yield, demonstrated with 22 examples in each case, is ...