Tetrahedron Letters

An expeditious, efficient green methodology for the Boc protection of amines and silyl protection of alcohols over tungstophosphoric acid-doped mesoporous silica

B Karmakar, J Banerji

文献索引：Karmakar, Bikash; Banerji, Julie Tetrahedron Letters, 2010 , vol. 51, # 29 p. 3855 - 3858

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被引用次数: 16

摘要

An efficient, chemoselective and eco-friendly protocol for the protection of amines as N-tert- butylcarbamate using (Boc) 2O and protection of alcohols as silyl ether using HMDS over tungstophosphoric acid/SBA15 has been developed. Solventless condition, easy work-up, short reaction time, excellent yields and reusability of the catalyst are the striking features of this methodology which can be considered to be one of the better methods for the ...