32 on the described 4-benzylanthranilic acids and benzisothiazoles equaled those of the previously reported'32 highceiling diuretics of the sulfamylanthranilic acid and 3- aminobenzoic acid series. In consideration of the absent free sulfonamide function, the high potency of the listed carboxybenzisothiazoles is rather interesting. However, a consideration of the following points led to an investigation into whether the diuretic activity should be ...