(E)-and (Z)-Di-tert-butyl 2-amino-3-fluoro-2-butene-1, 4-dioate [(E)-and (-021 were synthesized in two ways:(a) by elimination of hydrogen fluoride from di-tert-butyl p, P- difluoroaspartate under the influence of 1, 5-diazabicyclo [4.3. 0] non-5-ene and (b) by amination with the ammonium acetate of di-tert-butyl monofluorooxaloacetate (3), obtained via condensation of tert-butyl monofluoroacetate with di-tert-butyl oxalate. Reduction of 2 ...
