Synthesis, antitumor, and antimicrobial activity of N-substituted nitrofurylvinyl (butadienyl)-4-amino (hydrazino) quinolines

…, AA Zidermane, II Pelevina, SS Vornina

文献索引：Sukhova, N. M.; Lidak, M. Yu.; Zidermane, A. A.; Pelevina, I. I.; Vornina, S. S. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 10 p. 840 - 843 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 10 p. 1226 - 1229

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摘要

The nitrofurylvinylquinolines reported in the literature, with amino-, acetylamino-, chloro-, hydroxy-, ethoxy-, carboxy-, ethoxy-, carboxy-(sic-translator), or carbamoyl groups in the 3-, 4-, or 6-positions, were obtained only by the condensation of 2-methylquinoline or its derivatives with 5-nitrofurfural in acetic anhydride, acetic acid, or mixtures thereof [6, 7]. Attempts to obtain (1)-(XIV) by condensation resulted in the formation of small amounts ...