Abstract A new series of nitenpyram analogs were designed by introducing 1, 4- dihydropyridine to fix the pharmacophore (–C= C–NO 2) into the cis-configuration, as confirmed by X-ray diffraction. Crystal structure analysis showed that there was a homoconjugation effect on these cis-nitenpyram analogs, and a huge conjugated system comprising the 1, 4-dihydropyridine scaffold and the ester group at the 3 position. ...
