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Genotoxic activity of halogenated phenylglycine derivatives

…, M Menacho-Márquez, A Orjales, CJ Saavedra

文献索引:Boto, Alicia; Gallardo, Juan A.; Hernandez, Rosendo; Ledo, Francisco; Munoz, Ana; Murguia, Jose R.; Menacho-Marquez, Mauricio; Orjales, Aurelio; Saavedra, Carlos J. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6073 - 6077

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被引用次数: 7

摘要

The discovery of genotoxic amino acids derived from phenylglycine, and posessing halogen substituents, is described. The utility of hypervalent iodine reagents in the synthesis of this class of compounds is highlighted. The mechanism of action of the (haloaryl) glycines was ...