A formylation-cyclization method of synthesis of cycloalkenones from unsaturated ketones. 2. Simple synthesis of some functionalized bicyclo [3.3. 1] nonane …
The potential generality of formylation-cyclization of a variety of y, b-unsaturated methyl ketones as a route to some functionalized bicyclo [3.3. l] nonane derivatives has been examined. Thus, perchloric acid catalyzed reactions of 0-diethoxyethyl ketones 2a-c and 14a-c, derived from the 2-acetyl-2-methylhexahydrophenanthrenes and tetrahydrofluorenes la-c and 13a-c, respectively, in the absence and presence of triethyl orthoformate, afforded ...
