Journal of Heterocyclic Chemistry

Synthesis of 2??arylpyrido [3, 4??b] pyrazine derivatives through condensation of 3, 4??diaminopyridine with β??keto sulfoxides

S Kano, Y Yuasa

文献索引：Kano, Shinzo; Yuasa, Yoko Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 769 - 770

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被引用次数: 5

摘要

Abstract The reaction between 3, 4-diaminopyridine and α-methylsulfinylacetophenone in benzene containing acetic acid under reflux gave 2-phenylpyrido [3, 4-b] pyrazine. In this way, 2-(4-methoxyphenyl) pyrido [3, 4-b]-pyrazine and 2-(3, 4-dimethoxyphenyl) pyrido [3, 4- b] pyrazine were obtained by condensation of 3, 4-diaminopyridine with the corresponding α- methylsulfinylacetophenones.