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A convenient synthesis of sulfonylureas from carboxylic acids and sulfonamides via an in situ Curtius rearrangement

CA Luckhurst, I Millichip, B Parker, J Reuberson…

文献索引:Luckhurst, Christopher A.; Millichip, Ian; Parker, Beth; Reuberson, James; Furber, Mark Tetrahedron Letters, 2007 , vol. 48, # 50 p. 8878 - 8882

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被引用次数: 10

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A one-pot reaction of carboxylic acids with sulfonamides to afford sulfonylureas is described. ... This expedient synthesis of sulfonylureas from carboxylic acids and sulfonamides obviates the requirement to isolate isocyanates or similar intermediates. The methodology allows access to a wide ...