Synthesis of 2-hydroxy-8'-(hydroxymethyl)-1, 1'-binaphthalene (iso-homo-binol). A new structural pattern in the binaphthyl realm
…, SC Lockhart, WL Mitchell, P Kočovský
文献索引：Vyskocil, Stepan; Lockhart, Stephen C.; Mitchell, William L.; Kocovsky, Pavel Collection of Czechoslovak Chemical Communications, 2003 , vol. 68, # 5 p. 907 - 916
Abstract The title compound 7 has been synthesized in a racemic form, using Suzuki coupling (8+ 15→ 16) as the key step. Pure enantiomer (S)-(-)-7 has been obtained by carbonylation of the known bromide (S)-(+)-12 followed by reduction of the resulting methyl ester (S)-(+)-18 with LiAlH 4.
