Journal of heterocyclic chemistry

Synthesis of 5??phenyl??5, 6, 7, 8??tetrahydro??1, 6??naphthyridines and 5??phenyl??6, 7, 8, 9??tetrahydro??5H??pyrido [3, 2??c] azepines as potential D1 receptor ligands

T Hussenether, R Troschütz

文献索引：Hussenether, Thomas; Troschuetz, Reinhard Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 6 p. 857 - 865

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被引用次数: 12

摘要

Abstract A new access to 5-phenyl-5, 6, 7, 8-tetrahydro-1, 6-naphthyridines 25a-28a (n= 1) and 5-phenyl-6, 7, 8, 9-tetrahydro-5H-pyrido [3, 2-c] azepines 25b-28b (n= 2) has been developed by first preparing the functional pyridine moiety followed by intramolecular cyclization forming the partially reduced ring.