Tetrahedron Letters

InBr 3-catalyzed annulations of cyclic 1, 3-diketones with aryl propargyl alcohols: a novel synthesis of 2, 4-diaryldihydropyrans

JS Yadav, BVS Reddy, KVR Rao, R Narender

文献索引：Yadav; Subba Reddy; Raghavendra Rao; Narender Tetrahedron Letters, 2009 , vol. 50, # 27 p. 3963 - 3965

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被引用次数: 17

摘要

Lewis acid catalyzed carbon–carbon bond-forming reactions are of great significance in organic synthesis because of their high reactivity, selectivity, and mild reaction conditions. 1 Aryl propargyl methanols are well-known carbon electrophiles capable of reacting with various nucleophiles and their ability to undergo nucleophilic substitution reactions contributes largely to their synthetic value. 2 and 3 The direct nucleophilic substitution of the hydroxy group in alcohols with ...