Studies on the inhibition of tumor cell growth and microtubule assembly by 3-hydroxy-4-[(E)-(2-furyl) methylidene] methyl-3-cyclopentene-1, 2-dione, an intensively …
D Marko, M Kemeny, E Bernady, M Habermeyer…
文献索引：Marko, D; Kemeny, M; Bernady, E; Habermeyer, M; Weyand, U; Meiers, S; Frank, O; Hofmann, T Food and Chemical Toxicology, 2002 , vol. 40, # 1 p. 9 - 18
Very recently, 3-hydroxy-4-[(E)-(2-furyl) methylidene] methyl-3-cyclopentene-1, 2-dione (1) has been successfully identified as an intensively coloured Maillard product formed from glucose and l-proline upon thermal food processing. Using a biomimetic synthetic strategy, reference material of compound 1 was prepared and purified, and then used to study its effect on the growth of human tumor cells. Compound 1 was found to potently inhibit the ...
