First Synthesis of r ac-(5-2H3)-α-CEHC, a Labeled Analogue of a Major Vitamin E Metabolite

F Mazzini, T Netscher, P Salvadori

文献索引：Mazzini, Francesco; Netscher, Thomas; Salvadori, Piero Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9303 - 9306

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被引用次数: 5

摘要

Over the past few years, quantitative determination of α-and γ-CEHC, main urinary metabolites of vitamin E, has been becoming more and more important as a key parameter in assessing oxidative stress and supplementation of tocopherols. The use of deuterated analogues of these metabolites allows their accurate determination even in complex matrixes. While preparation of γ-CEHC-d 2 has already been described, here we report ...