Chinese Chemical Letters

PEG-OSO 3 H as an efficient and recyclable catalyst for the synthesis of β-amino carbonyl compounds via the Mannich reaction in PEG–H 2 O

XC Wang, LJ Zhang, Z Zhang, ZJ Quan

文献索引：Wang, Xi Cun; Zhang, Li Jia; Zhang, Zhang; Quan, Zheng Jun Chinese Chemical Letters, 2012 , vol. 23, # 4 p. 423 - 426

全文：HTML全文

被引用次数: 17

摘要

Sulfuric acid-modified polyethylene glycol 6000 (PEG-OSO3H) was applied as an efficient and recyclable catalyst for the synthesis of β-amino carbonyl compounds via the Mannich reaction between aldehydes, aromatic ketones and aromatic amines at room temperature using PEG400–H2O (1: 1) as environment-friendly solvents. The reactions were completed in short times and mild reaction conditions with good to excellent yields.