Optically active nitrogen ligands. 1. Synthesis of two optically active monoalkyl-substituted 2-(2-pyridyl) pyridines

C Botteghi, G Caccia, G Chelucci…

文献索引：Botteghi, C.; Caccia, G.; Chelucci, G.; Soccolini, F. Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4290 - 4293

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被引用次数: 34

摘要

For the conversion of 10 into 2, hydroxylamine hydrochloride in dry acetic acid was found to be the best reagent15: up to 40% yield of 2 was reached by heating 10 under these conditions for 6 h (Scheme 11). The main byproduct (23%) of this reaction was unsubstituted 2-(2'-pyridyl) pyridine, which was isolated and identified by comparison of its MS and NMR spectra with those of an authentic sample. This compound is formed presumably by ...