Organic letters

A Practical Preparation of Highly Versatile N-Acylpyrroles from 2, 4, 4-Trimethoxybutan-1-amine

T Maehara, R Kanno, S Yokoshima, T Fukuyama

文献索引：Maehara, Tomoaki; Kanno, Rentaro; Yokoshima, Satoshi; Fukuyama, Tohru Organic Letters, 2012 , vol. 14, # 7 p. 1946 - 1948

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被引用次数: 19

摘要

A novel method for the preparation of N-acylpyrrole is described. The method involves condensation of carboxylic acids with 2, 4, 4-trimethoxybutan-1-amine, followed by acid- mediated cyclization to form the pyrrole ring. The preparative procedure is highly tolerant of a variety of functional groups.