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Carbohydrate research

Synthesis and reactions of 1-(5-azido-5-deoxy-3-Op toluenesulfonyl-β-d-xylofuranosyl) derivatives of 5-alkyl-and 5-halo-pyrimidines

NA Al-Masoudi, W Pfleiderer

文献索引:Al-Masoudi, Najim A.; Pfleiderer, W. Carbohydrate Research, 1995 , vol. 275, # 1 p. 95 - 106

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被引用次数: 5

摘要

Chemical syntheses of 1-(2-O-acetyl-5-azido-5-deoxy-3-Op-toluenesulfonyl-β-d- xylofuranosyl)-5-iodo-,-5-fluoro-, and-5-trifluoromethyl-uracil nucleosides (11–13) as well as the thymine analogue 10 were performed from a sugar precursor and the corresponding uracil bases. Partial deblocking of 10–13 gave the 5′-azido-5′-deoxynucleosides 14–17. The 3′, 5′-diazido-3′, 5′-dideoxyribonucleosides were obtained in the same way. ...