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Synthesis of 2-N-salicylidene-5-(substituted)-1, 3, 4-thiadiazole as potential antimicrobial agents

J Salimon, N Salih, H Ibraheem…

文献索引:Salimon, Jumat; Salih, Nadia; Ibraheem, Hanan; Yousif, Emad Asian Journal of Chemistry, 2010 , vol. 22, # 7 p. 5289 - 5296

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被引用次数: 18

摘要

Abstract Several new 2, 5-disubstituted derivatives of 1, 3, 4-thiadiazoles containing imine moiety were obtained from cyclization of thiosemicarbazide and corresponding p-substituted carboxylic acid in phosphorus oxychloride then the resulted products were reacted with salicylaldehyde to give the final products 3a-h. All the newly synthesized compounds were characterized using FTIR, 1H NMR, 13C NMR and elemental analysis. All compounds ...