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The Mitsunobu Reaction of Tetrachlorophthalimide

…, S Kelberlau, L Olsson, G Anilkumar, B Fraser-Reid

文献索引:Jia, Zhaozhong J.; Kelberlau, Sandra; Olsson, Lars; Anilkumar; Fraser-Reid, Bert Synlett, 1999 , # 5 p. 565 - 566

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被引用次数: 10

摘要

Abstract: Tetrachlorophthalimide is shown to be an excellent agent for Mitsunobu displacement of primary hydroxyl groups in a wide variety of substrates. Secondary alcohols also react readily, except in carbohydrate derivatives where there is a low rate of success. In a competition experiment between phthalimide and its tetrachloro counterpart, there was no trace of a product from the former. Key words: Mitsunobu, tetrachlorophthalimide, hydroxyl ...