Abstract A general synthetic route to N-1-(2, 2-dichloroalkylidene) amides is described, starting from aliphatic 2, 2-dichloroaldehydes and an appropriate N-unsubstituted amide. The adducts thus formed were converted into N-(1, 2, 2-trichloroalkyl) amides with thionylchloride and subsequently dehydrohalogenated with triethylamine. These N-acyl α, α- dichloroaldimines were found to be very apt to nucleophilic addition at the activated ...
