Synthetic approaches to haplophytine. 1. Synthesis of 1-methoxy-and 1-hydroxy-6-phenyl-6-(2-pivaloylamidophenyl) non-8-ene-4, 5-dione and 1-methyl-3-phenyl-3-( …
P Yates, DA Schwartz
文献索引：Yates, Peter; Schwartz, David Aaron Canadian Journal of Chemistry, 1983 , vol. 61, p. 509 - 518
An analysis of the structures of the alkaloid haplophytine and its dihydrobromide which is formed with rearrangement, shows that they are both derived from a 7-(2-amino-3- hydroxyphenyl)-7-aryl-9-(methylamino)-5, 6-dioxononanoic acid moiety (3). Approaches to the synthesis of compounds related to 3 are described. The dianion 13 of phenyl (2- pivaloylamidophenyl) methane, that of methyl 2-phenyl-2-(2-pivaloylamidophenyl) acetate ...
