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Use of a Base-Labile Protected Derivative of 6-Mercaptohexanol for the Preparation of Oligonucleotides Containing a Thiol Group at the 5′-End

BG de la Torre, AM Aviñó, M Escarceller…

文献索引:Nucleosides and Nucleotides, , vol. 12, # 9 p. 993 - 1005

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被引用次数: 12

摘要

Page 1. NUCLEOSIDES & NUCLEOTIDES, 12(9), 993-1005 (1993) ... acid analysis (see FIG. 4). Overall yield (from the first nucleoside attached to the CPG support to purified hybrid molecules) was 15%, that is ten times higher than ...