Tetrahedron letters

Chiral 1, 3-cyclobutane amino acids: Syntheses and extended conformations

K Burgess, S Li, J Rebenspies

文献索引：Burgess, Kevin; Li, Shiming; Rebenspies, Joe Tetrahedron Letters, 1997 , vol. 38, # 10 p. 1681 - 1684

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被引用次数: 45

摘要

Optically active samples of the N-protected 1, 3-cyclobutane amino acids 1 and 2 were prepared from α-pinene. The synthesis of 1 is enantiodivergent insofar as both optical antipodes of the product can be prepared from the same α-pinene enantiomer. Single crystal X-ray diffraction studies of derivatives of 1 reveal these compounds can have extended conformations.