Tetrahedron letters

Synthesis of macrocyclic lactams and lactones via ring-closing olefin metathesis

WPD Goldring, AS Hodder, L Weiler

文献索引：Goldring, William P. D.; Hodder, Andre S.; Weiler, Larry Tetrahedron Letters, 1998 , vol. 39, # 28 p. 4955 - 4958

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被引用次数: 53

摘要

A&Wrack Lactones and lactams 4-6 were synthesized from a series of acyclic dienes 1-3 via ringclosing olefin metathesis, as shown in equation 1. The geometry of the resulting double bond was determined, and the UZratios compared to values from molecular mechanics calculations. 0 1998 Elsevier Science Ltd. All rights reserved.