Total Synthesis of Umuravumbolide and Hyptolide Through Silicon??Tethered Ring??Closing Metathesis

PS Chowdhury, P Kumar

文献索引：Chowdhury, Partha Sarathi; Kumar, Pradeep European Journal of Organic Chemistry, 2013 , # 21 p. 4586 - 4593

全文：HTML全文

被引用次数: 1

摘要

Abstract The total synthesis of umuravumbolide and hyptolide has been achieved in a efficient manner by using temporary silicon-tethered ring-closing metathesis and cross- coupling reactions as key steps. The stereogenic centres were generated by means of proline-catalysed α-aminoxylation of aldehydes and Brown's asymmetric allylation method.