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Tetrahedron

Synthesis and reactivity of N-alkyl-2-oxoalkanesulfonamides

JA Vega, R Alajarín, JJ Vaquero, J Alvarez-Builla

文献索引:Vega, Juan A.; Alajarin, Ramon; Vaquero, Juan J.; Alvarez-Builla, Julio Tetrahedron, 1998 , vol. 54, # 14 p. 3589 - 3606

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被引用次数: 5

摘要

A series of N-alkyl-2-oxoalkanesulfonamides have been synthesized by reacting silyl enol ethers with N-alkyl-sulfamoyl chlorides. Their reactivity towards electrophiles was investigated in order to explore the regio-aand stereoselectivity of the process. 2- Oxoalkanesulfonamides were used to prepare 5-(methylsulfamoyl)-1, 4-dihydropyridines derivatives.