Chiral Diphosphane??and NHC??Containing Ruthenium Catalysts for the Catalytic Asymmetric Arylation of Aldimines with Organoboron Reagents

CS Marques, AJ Burke

文献索引：Marques, Carolina S.; Burke, Anthony J. European Journal of Organic Chemistry, 2012 , # 22 p. 4232 - 4239

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被引用次数: 5

摘要

Abstract For the first time, we report the application of [RuCl 2 (η 6-p-cymene)] 2 in the arylation of N-activated aldimines with boronic acids and its derivatives to afford chiral amines, which are important intermediates in the syntheses of key bioactive compounds. The behavior of the chiral ligands, the imine substrates, and the organoboron reagents were studied. Very good enantioselectivities were obtained.