Abstract The development of value-added wood-derived polymer products is of significant importance. Of particular interest is the synthesis of advanced bioactive cellulosic materials. In the present research, novel cellulosic honeycomb films are reported. Cellulose was reacted with dimethylthexylsilyl chloride to form regioselective 2, 6-di-O-thexyldimethylsilyl cellulose followed by substitution of the C3 with functionalized poly (ethylene glycol)(PEG) ...