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Organic letters

Efficient and regiospecific one-pot synthesis of substituted 1, 2, 4-triazoles

MJ Stocks, DR Cheshire, R Reynolds

文献索引:Stocks, Michael J.; Cheshire, David R.; Reynolds, Rachel Organic Letters, 2004 , vol. 6, # 17 p. 2969 - 2971

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被引用次数: 61

摘要

Many 1,2,4-triazoles are of biological interest, 1 and as a consequence, a number of synthetic methods have been developed to construct this ring system. 2 To date, there have been no viable one-pot convergent syntheses reported. We wish to communicate our initial work for an efficient one-pot synthesis of substituted 1,2,4-triazoles 1, employing readily available starting materials. ... We envisaged that substituted 1,2,4-triazoles 1 could be obtained from the ...