Tetrahedron

A serendipitous conversion of enaminolactone nitriles with primary amines: a new synthesis of substituted 2-aminopyridine derivatives

…, N Choukchou-Braham, B Mostefa-Kara, J Sopkova

文献索引：Cheikh, Nawel; Villemin, Didier; Bar, Nathalie; Lohier, Jean-Francois; Choukchou-Braham, Nourredine; Mostefa-Kara, Bachir; Sopkova, Jana Tetrahedron, 2013 , vol. 69, # 3 p. 1234 - 1247

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被引用次数: 4

摘要

In the course of our studies on Cerpegin analogues synthesis, a serendipitous reactivity of enaminolactone nitrile has been observed. Instead of expecting iminocerpegins, we have gained new class of substituted 2-aminopyridines. The methodology has been applied on a wide range of primary amines, as aliphatic, aromatic, heteroaromatic and also, diamines, hydrazines and chiral amines.