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Synthesis of 3??hydroxy??4??imidazolidinones

RE Harmon, VL Rizzo, SK Gupta

文献索引:Harmon,R.E. et al. Journal of Heterocyclic Chemistry, 1970 , vol. 7, p. 439 - 442

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被引用次数: 12

摘要

So far very little work has been reported on the preparation and properties of 4imidazolidinones 1. The known methods involve reduction of either thiohydantoins 2 (2) or 4'(5)-imidazolones 3 (3). In this paper we wish to report a rather convenient synthesis of 3- hydroxy-4imidazolidinones (6a-61), which is based on the reaction of aliphatic a- aminohydroxamic acids with aromatic aldehydes.