N-Alicyclic-substituted derivatives of 2-aminoethanethiol and related compounds as antiradiation agents

RD Elliott, JR Piper, CR Stringfellow…

文献索引：Elliott,R.D. et al. Journal of Medicinal Chemistry, 1972 , vol. 15, p. 595 - 600

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被引用次数: 5

摘要

A number of 2-aminoethanethiol derivatives, RNH (CH&SY, in which R is an alicyclic or heteroalicyclic group and SY is a suitable S function (eg, thiol, thiosulfate, or phosphorothioate), were synthesized for evaluation as antiradiation agents. The intermediate N-substituted 2-bromoethylamines were prepared from either 3-substituted 2- oxazolidinones derived from primary amines or N-substituted 2-aminoethanols derived ...