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Tetrahedron letters

Enantioselective deprotonation of two racemic cyclic carbonyl compounds by a chiral lithium amide

MB Eleveld, H Hogeveen

文献索引:Eleveld, M. B.; Hogeveen, H. Tetrahedron Letters, 1986 , vol. 27, # 5 p. 631 - 634

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被引用次数: 43

摘要

Abstract: The cyclic carbonyl compounds 2 and 8 have been obtained in optical active form (0.~. 46% and 36X, respectively) from the racemic compounds by a deprotonation/ protonation sequence, using chiral lithium amide 1. The optical activity of 2 is caused by a difference in the deprotonation rates of the enaztiomers.