A novel series of selective leukotriene antagonists: exploration and optimization of the acidic region in 1, 6-disubstituted indoles and indazoles

YK Yee, PR Bernstein, EJ Adams…

文献索引：Journal of Medicinal Chemistry, , vol. 33, # 9 p. 2437 - 2451

全文：HTML全文

被引用次数: 60

摘要

... A major pharmaceutical goal has been the discovery and develop- ment of novel, selective antagonists of the leukotrienes as potential therapeutic agents for the treatment of asthma. ... Page 2. 2438 Journal of Medicinal Chemistry, 1990, Vol. 33, No. 9 Scheme I ...