Novel cyclonucleoside analogues of uridine having pentylene and hexylene linker between the 5′-O and 3-N positions (thereby generating a 13-and 14-membered ring, respectively) were synthesized from uridine via ring-closing metathesis. An example of cyclic dinucleosides having two butylene linkers between the 5′-O and 3-N positions (24- membered ring) was synthesized from uridine via tandem cross-metathesis and ring- ...
