Derivatives of arylalkylamines. XXIII. Synthesis of N-arylalkyl-substituted 3-[2, 3 (or 2, 4)-dihydroxyphenyl]-3-phenylpropylamines and their effect on the uptake of …
…, MG Akopyan, RM Vartanyan, AA Kaltrikyan…
文献索引：Balayan, R. S.; Akopyan, M. G.; Vartanyan, R. M.; Kaltrikyan, A. A.; Avakyan, O. M.; et al. Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 8 p. 558 - 562 Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 8 p. 956 - 960
Certain derivatives of diphenylpropylamine have sympatho- and andrenolytic activity and block the uptake of catecholamines [2, 7, 9, i0]. This served as a basis for the syn- thesis of new compounds (Via-j) containing two hydroxy I groups in one of the aromatic rings of the diphenyl fragment, and a study of their action on the uptake of catecholamines, liberation of a mediator from the sympathetic nerve extremities, and on ~-adrenoreceptors. Compounds VIa-j were ...
